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Correlation between RNA fragments of fowl plague virus and their corresponding gene functions

Identifieur interne : 002B29 ( Main/Exploration ); précédent : 002B28; suivant : 002B30

Correlation between RNA fragments of fowl plague virus and their corresponding gene functions

Auteurs : C. Scholtissek [Allemagne] ; Etti Harms [Allemagne] ; W. Rohde [Allemagne] ; Michaela Orlich [Allemagne] ; R. Rott [Allemagne]

Source :

RBID : ISTEX:8E8961D575ECE80272DF27FCA76CE9420B5DAEBD

English descriptors

Abstract

Abstract: Fowl plague virus (FPV) RNA consists of eight fragments which, except for the two fragments with the highest molecular weight, can be clearly separated by polyacrylamide gel electrophoresis in the presence of 8 M urea. The base sequence homology between individual fragments of FPV RNA and the complementary RNA (cRNA) of various influenza A prototype strains has been established. Recombinants have been isolated by double infection of chick embryo cells with ts mutants of FPV and influenza A strains, which do not form plaques on this host. By hybridization of the cRNA of these recombinants with the 32P-labeled fragments of FPV RNA six of the eight RNA fragments can be correlated with gene functions of FPV.

Url:
DOI: 10.1016/0042-6822(76)90340-8


Affiliations:


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Le document en format XML

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